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“Heart-Breaking” Assisted Reproductive Technology: Successful Pregnancy After an Intracytoplasmic Sperm Injection Procedure Complicated by Acute Myocardial Infarction of the Male Partner

Sometimes even conditions that could be prologue to tragedy may turn out to have a happy ending. The couple we had in care was composed by a 36 years old woman in general good health and a 42 years old man in good conditions despite being an average smoker and having arterial hypertension. Since first level Assisted Reproductive Technology (ART) was unsuccessful, we proceeded to Intracytoplasmic Sperm Injection (ICSI) with the indication of mild male factor infertility. On day 9 of the second ICSI cycle, the male partner complained typical myocardial pain. The patient was hospitalized for a myocardial infarction and underwent a percutaneous trans-luminal coronary angioplasty during which three stents where placed. We deemed relevant reporting this case: despite the male partner of this couple experienced the misfortune of a myocardial infarction during a cycle of ART, he still successfully accomplished to collect his semen for oocytes fecundation. The cycle was therefore happily brought to an end with the implantation and the on-going progression of a dichorionic diamniotic twin pregnancy.


Cirillo F, Zannoni E, Heilbron F, Pagnotta P, Canevisio V, Sacchi L and Levi-Setti PE

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