Journal of Reproductive Endocrinology & Infertility

Goserelin vs. Other Treatments in Pain Symptoms Related to Endometriosis after Surgery: An Evidence-Based Case Report

Background: The aim of this case study is to know the efficacy of goserelin for pain treatment in endometriosis.

Methods: In this case report, the clinical question is about the treatment of endometriosis, which pain reliever give better outcome to decrease the pain; goserelin or other treatments. To answer this question, we did a searching in PubMed site by using three keywords using MESH, namely ("Goserelin"[Mesh]) and "Pain"[Mesh]) AND "Endometriosis"[Mesh]. Apart from that, we also searched in the Cochrane database by using MeSH descriptor: [Pain] explode all trees AND MeSH descriptor: [Endometriosis] explode all trees AND MeSH descriptor: [Goserelin].

Results: From the searching literature, we found 22 articles which were relevant to the topic. After screening the abstract and language, we got 4 articles to be appraised.

Conclusion: Based on evidences, goserelin was comparable with other treatments. The most common side effect of GnRH was vasomotor symptoms and amenorrhea but that did not reduce patient satisfaction. No serious side effect was observed in goserelin treatment group. 

Author(s):

Harzif AK, Handoko Y*, Nanda A, Nilasari D, Nurliana I and Ratna Pratamasari SM

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